Opis oferty:

Science and Matrix Lead in the environment of Advanced Cell-based Assays for Drug Discovery (m/f/d) ; At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. 

The position is located in the Immune  and Cell Biology Department, within the Discovery unit  of pRED’s Large Molecules Research, where the discovery and development of next generation biotherapeutics is the primary focus. We closely collaborate with disease therapeutic areas and other functions to convert therapeutic hypotheses into innovative therapeutics.

In this environment, we are seeking an experienced Science and Matrix Leader (m/f/d) with a strong scientific background in immune and cell biology, and a specific focus on immunology, neuroscience and/or ophthalmology. The role requires significant industrial experience in drug discovery and development, encompassing the entire journey from target assessment to Entry into Human.  You will expertly lead cross-functional teams, contribute to portfolio projects, and drive the implementation of cutting-edge cell-based functional assays to discover and characterize large molecule-based therapeutics. 

Wymagania:

• Extensive industrial experience in large-molecule drug discovery, in particular leading cell-based assay development for therapeutic candidate selection in physiologically relevant model systems, including primary cells, iPSCs, organs-on-a-chip, and organoids
• Solid experience in  assay readout technologies such as flow cytometry (including multiparameter and AMNIS technology), live-cell imaging (such as incucyte) and advanced fluorescence microscopy (confocal, super-resolution, FLIM, smFISH, and high-content imaging)
• You have specific background in cell biology, immunology, neuroscience and or ophthalmology
• A PhD in biology or other relevant fields  is the base of your knowledge
• A keen interest in working with IT systems  for multiparameter data analysis in (semi-) automated workflows. Experience with  high-throughput screening platforms and large data analysis is an asset
• Demonstrated ability to lead and inspire highly engaged matrix teams, ideally as a project leader in drug discovery projects
• Proven scientific expertise through documented contributions or publications in high impact journals in your scientific or technical field
• You are resourceful and flexible in problem solving and in working in a collaborative and inclusive manner with strong oral and written communication skills